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方案
≥98% (HPLC)
表单
powder
颜色
white to very dark brown
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
InChI
1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
InChI key
CRGKLHXVNVZAPA-UHFFFAOYSA-N
生化/生理作用
RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.
potent inhibitor of the replication licensing system.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
历史批次信息供参考:
Nicola J Gardner et al.
Cell chemical biology, 24(8), 981-992 (2017-08-07)
In late mitosis and G
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