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Merck
CN

SML2169

Sigma-Aldrich

地芬尼多 盐酸盐

≥98% (HPLC)

别名:

1,1-二苯基-4-(1-哌啶基)-1-丁醇, 戴芬逸多

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About This Item

经验公式(希尔记法):
C21H27NO · HCl
CAS号:
分子量:
345.91
EC 号:
MDL编号:
UNSPSC代码:
12352100
NACRES:
NA.77

检测方案

≥98% (HPLC)

形式

powder

储存条件

desiccated

颜色

white to beige

溶解性

H2O: 2 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES字符串

Cl.OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3

InChI

1S/C21H27NO.ClH/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22;/h1-2,4-7,11-14,23H,3,8-10,15-18H2;1H

InChI key

AVZIYZHXZAYGJS-UHFFFAOYSA-N

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生化/生理作用

Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist. Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Lin Zhang et al.
Forensic science, medicine, and pathology, 11(4), 570-576 (2015-10-21)
Diphenidol hydrochloride (DPN), a nonphenothiazinic antiemetic agent used primarily in patients with Meniere disease and labyrinthopathies to treat vomiting and vertigo, is considered to be a relatively safe drug. Since it was first approved in the United States in 1967
Yu-Wen Chen et al.
Neuroscience letters, 552, 62-65 (2013-08-07)
Diphenidol has been shown to block voltage-gated Na(+) channels, which are associated with specific types of pain. Here, we evaluated the effects of diphenidol on chronic constriction injury (CCI)-evoked allodynia and expression of tumor necrosis factor-α (TNF-α). A peripheral nerve

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