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Merck
CN

SML2132

Sigma-Aldrich

巴西木素

别名:

苏枋精, (+)-Brazilin, 7,11b-二氢苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, NSC 56652, (6aS,11bR)-7,11b-二氢-苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, 6,6a,7,11b-四氢-3,6a,9,10-四羟基茚并[2,1-c]色烯, 天然红24

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About This Item

经验公式(希尔记法):
C16H14O5
CAS号:
分子量:
286.28
颜色索引号:
75280
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

颜色

white to very dark brown

溶解性

DMSO: 2 mg/mL

储存温度

2-8°C

InChI

1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1

InChI key

UWHUTZOCTZJUKC-JKSUJKDBSA-N

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生化/生理作用

巴西木素是一种天然的异黄酮类红色素,具有许多生物学活性,包括神经保护、抗炎、抗菌、抗增殖和抗氧化特性。人们认为其某些活性是由于其对转录因子NF-ΚB的调节.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Zhan-Yuan Li et al.
Inflammation, 40(4), 1365-1374 (2017-05-13)
Hyperglycemia and inflammation play important roles in the pathogenesis of diabetic nephropathy (DN). Brazilin might be an effective pharmacological agent against hyperglycemia and inflammation. In our present study, we explored whether brazilin mitigated pathological progression, inflammation, and extracellular matrix (ECM)
Yanyan Jia et al.
International journal of molecular medicine, 38(1), 210-216 (2016-06-02)
Renal ischemia-reperfusion (I/R) injury is associated with high morbidity and mortality as there is currently no available effective therapeutic strategy with which to treat this injury. Thus, the aim of this study was to investigate the potential protective effects of
Eun Byeol Lee et al.
Archives of pharmacal research, 40(7), 825-835 (2017-07-02)
This study contributes to the continual discovery of lifespan-extending compounds from plants, using the Caenorhabditis elegans model system. An ethyl acetate soluble fraction of methanol extract from the heartwood of Caesalpinia sappan showed a significant lifespan-extending activity. Subsequent activity-guided chromatography

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