SML2132
巴西木素
别名:
苏枋精, (+)-Brazilin, 7,11b-二氢苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, NSC 56652, (6aS,11bR)-7,11b-二氢-苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, 6,6a,7,11b-四氢-3,6a,9,10-四羟基茚并[2,1-c]色烯, 天然红24
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所有图片(1)
About This Item
经验公式(希尔记法):
C16H14O5
CAS号:
分子量:
286.28
颜色索引号:
75280
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
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旋光性
[α]/D 108.0 to 133.0°, c = 0.5 in methanol
颜色
white to very dark brown
溶解性
DMSO: 2 mg/mL
储存温度
2-8°C
SMILES字符串
O1C[C@]2([C@@H](c4c1cc(cc4)O)c3c(cc(c(c3)O)O)C2)O
InChI
1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1
InChI key
UWHUTZOCTZJUKC-JKSUJKDBSA-N
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生化/生理作用
巴西木素是一种天然的异黄酮类红色素,具有许多生物学活性,包括神经保护、抗炎、抗菌、抗增殖和抗氧化特性。人们认为其某些活性是由于其对转录因子NF-ΚB的调节.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Yanyan Jia et al.
International journal of molecular medicine, 38(1), 210-216 (2016-06-02)
Renal ischemia-reperfusion (I/R) injury is associated with high morbidity and mortality as there is currently no available effective therapeutic strategy with which to treat this injury. Thus, the aim of this study was to investigate the potential protective effects of
Zhan-Yuan Li et al.
Inflammation, 40(4), 1365-1374 (2017-05-13)
Hyperglycemia and inflammation play important roles in the pathogenesis of diabetic nephropathy (DN). Brazilin might be an effective pharmacological agent against hyperglycemia and inflammation. In our present study, we explored whether brazilin mitigated pathological progression, inflammation, and extracellular matrix (ECM)
Eun Byeol Lee et al.
Archives of pharmacal research, 40(7), 825-835 (2017-07-02)
This study contributes to the continual discovery of lifespan-extending compounds from plants, using the Caenorhabditis elegans model system. An ethyl acetate soluble fraction of methanol extract from the heartwood of Caesalpinia sappan showed a significant lifespan-extending activity. Subsequent activity-guided chromatography
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