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Merck
CN
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文件

安全信息

SML2072

Sigma-Aldrich

OX03050

≥98% (HPLC)

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别名:
(E)-3-(4-Styrylphenoxy)propan-1-ol, 3-[4-[(1E)-2-Phenylethenyl]phenoxy]-1-propanol
经验公式(希尔记法):
C17H18O2
分子量:
254.32
UNSPSC代码:
12352200
NACRES:
NA.77

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

生化/生理作用

OX03050 is a metabolically stable, potent and selective squalene synthase inhibitor that upregulates the Low-Density Lipoprotein Receptor (LDLR) in mouse and in human liver cell lines. OX03050 used in conjunction with statin acts synergistically to increase LDLR expression

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Alastair G Kerr et al.
The Journal of pharmacology and experimental therapeutics, 361(3), 417-428 (2017-04-01)
Hypercholesterolemia remains one of the leading risk factors for the development of cardiovascular disease. Many large double-blind studies have demonstrated that lowering low-density lipoprotein (LDL) cholesterol using a statin can reduce the risk of having a cardiovascular event by approximately

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