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Merck
CN
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文件

安全信息

SML2063

Sigma-Aldrich

Davunetide trifluoroacetate salt

≥95% (HPLC)

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别名:
AL-108, Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln, L-Asparaginyl-L-alanyl-L-prolyl-L-valyl-L-seryl-L-isoleucyl-L-prolyl-L-Glutamine, NAP, NAP peptide, NAPVSIPQ
经验公式(希尔记法):
C36H60N10O12 · xC2HF3O2
分子量:
824.92 (free base basis)
UNSPSC代码:
12352200
NACRES:
NA.77

检测方案

≥95% (HPLC)

形式

powder

组成

Peptide content, ≥60%

颜色

white to beige

运输

wet ice

储存温度

−20°C

InChI

1S/C36H60N10O12/c1-6-18(4)28(35(56)46-14-8-9-23(46)31(52)41-21(36(57)58)11-12-25(38)48)44-30(51)22(16-47)42-33(54)27(17(2)3)43-32(53)24-10-7-13-45(24)34(55)19(5)40-29(50)20(37)15-26(39)49/h17-24,27-28,47H,6-16,37H2,1-5H3,(H2,38,48)(H2,39,49)(H,40,50)(H,41,52)(H,42,54)(H,43,53)(H,44,51)(H,57,58)/t18-,19-,20-,21-,22-,23-,24-,27-,28-/m0/s1

InChI key

DWLTUUXCVGVRAV-XWRHUKJGSA-N

生化/生理作用

Davunetide (NAPVSIPQ; NAP) is an eight amino acid peptide identified as the active component of activity-dependent neuroprotective protein (ADNP). It has been found to be neuro-protective at femtomolar concentrations in vitro against the neural toxicity of a wide range of compounds. Davunetide has been investigated for Parkinson′s disease and schizophrenia and in clinical trials for Alzheimner′s Disease, targeting microtubule-tau Interaction.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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