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Merck
CN

SML2023

Sigma-Aldrich

UCSF924NC

≥98% (HPLC)

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别名:
6-Methyl-2-((3-(pyridin-4-yl)propylamino)methyl)quinolin-4(1H)-one
经验公式(希尔记法):
C19H21N3O
分子量:
307.39
UNSPSC代码:
51111800
NACRES:
NA.77

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

−20°C

SMILES字符串

CC1=CC2=C(NC(CNCCCC3=CC=NC=C3)=CC2=O)C=C1

相关类别

生化/生理作用

UCSF924NC (Compound 9-6-16; ZINC000091707446) is the recommended negative control compound for the high-affinity dopamine D4 receptor (DRD4) partial agonist UCSF924 (Compound 9-6-24; ZINC000091726127). UCSF924NC exhibits a 1/2500-fold reduced D4 affinity when compared with that of UCSF924.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Sheng Wang et al.
Science (New York, N.Y.), 358(6361), 381-386 (2017-10-21)
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and

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