SML2013
RU 24969 hemisuccinate
≥98% (HPLC)
别名:
1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-, butanedioate (2:1), 5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-Indole hemisuccinate, 5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hemisuccinate
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所有图片(1)
About This Item
经验公式（希尔记法）:
C14H16N2O · 0.5C4H6O4
CAS号:
分子量:
287.33
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
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方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
yellow to yellow-orange
溶解性
H2O: 2 mg/mL, clear (warmed)
运输
ambient
储存温度
room temp
SMILES字符串
COC1=CC2=C(NC=C2C3=CCNCC3)C=C1.OC(CCC(O)=O)=O.COC4=CC5=C(NC=C5C6=CCNCC6)C=C4
InChI
1S/2C14H16N2O.C4H6O4/c2*1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10;5-3(6)1-2-4(7)8/h2*2-4,8-9,15-16H,5-7H2,1H3;1-2H2,(H,5,6)(H,7,8)
InChI key
BNYJLRQAWCQJOM-UHFFFAOYSA-N
生化/生理作用
RU-24969 is a potent and selective agonist at the 5-HT1A and 5-HT1B receptors.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Dane Aronsen et al.
Pharmacology, biochemistry, and behavior, 124, 1-4 (2014-05-23)
RU 24969 is a widely used, but non-selective, 5-HT1B/1A agonist that decreases fluid consumption and increases forward locomotion. The mechanism underlying these behavioural responses is not, however, well understood. Accordingly, effects of the selective 5-HT1A and 5-HT1B antagonists, WAY 100635
Dane Aronsen et al.
Psychopharmacology, 233(8), 1339-1347 (2016-02-10)
3,4 Methylenedioxymethamphetamine (MDMA) preferentially stimulates the release of serotonin (5-HT) that subsequently produces behavioral responses by activation of post-synaptic receptor mechanisms. The 5-HT1A and 5-HT1B receptors are both well localized to regulate dopamine (DA) release, and have been implicated in
Emily V Ho et al.
Psychopharmacology, 233(1), 57-70 (2015-10-02)
Serotonin-1B receptor (5-HT1BR) agonist treatment induces obsessive-compulsive disorder (OCD)-like behaviors including locomotor stereotypy, prepulse inhibition deficits, and delayed alternation disruptions, which are selectively prevented by clinically effective OCD treatment. However, the role of 5-HT1BRs in modulating other repetitive behaviors or
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