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Merck
CN

SML1968

Sigma-Aldrich

芬特明 盐酸盐

≥98% (HPLC)

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别名:
α,α-二甲基苯乙胺 盐酸盐
经验公式(希尔记法):
C10H15N · HCl
CAS号:
分子量:
185.69
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

H2O: 2 mg/mL, clear

储存温度

2-8°C

SMILES字符串

Cl.CC(C)(N)Cc1ccccc1

InChI

1S/C10H15N.ClH/c1-10(2,11)8-9-6-4-3-5-7-9;/h3-7H,8,11H2,1-2H3;1H

InChI key

NCAIGTHBQTXTLR-UHFFFAOYSA-N

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生化/生理作用

Phentermine is a sympathomimetic that releases norepinephrine and epinephrine in CNS and periphery reducing hunger. Similarly to other amphetamines, phentermine potently inhibits DA and 5-HT uptake.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Candida J Rebello et al.
Advances in therapy, 33(11), 1853-1866 (2016-10-28)
The homeostatic controls over eating are inextricably linked to the reward aspects of eating. The result is an integrated response that coordinates the internal milieu with the prevailing environment. Thus, appetite, which reflects a complex interaction among the external environment
Mark J Ferris et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(7), 1708-1716 (2012-03-08)
The dopamine transporter (DAT) is the primary site of action for psychostimulant drugs such as cocaine, methylphenidate, and amphetamine. Our previous work demonstrated a reduced ability of cocaine to inhibit the DAT following high-dose cocaine self-administration (SA), corresponding to a
B Kalyanasundar et al.
Journal of neurophysiology, 114(1), 585-607 (2015-05-15)
Obesity is a worldwide health problem that has reached epidemic proportions. To ameliorate this problem, one approach is the use of appetite suppressants. These compounds are frequently amphetamine congeners such as diethylpropion (DEP), phentermine (PHEN), and bupropion (BUP), whose effects

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