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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
H2O: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl
InChI
1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H
InChI key
RVKVVMXTPQCCIX-UHFFFAOYSA-N
生化/生理作用
3-3-碘类甲腺质(T1AM)存在于脊椎动物组织和循环系统中。其生理作用与甲状腺激素相反。T1AM既是一种神经调节剂,也是一种激素样分子。
T1AM(3-3-碘类甲腺质)是一种源自甲状腺激素的内源性生物胺。
T1AM(3-3-碘类甲腺质)是一种源自甲状腺激素的内源性生物胺。 T1AM是痕量胺相关受体TAAR1 (TAR1, Ta1)的强效激动剂,而 TAAR1 是一种主要在大脑中发现的 GPCR。
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
历史批次信息供参考:
分析证书(COA)
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 439-449 (2016-10-25)
Human trace amines (TAs) are endogenous compounds, previously almost ignored in human pathology for many reasons (difficulty of their measurement in biological fluids, unknown receptors for elusive amines), are now considered to play a significant role in synaptic transmission within
Molecular bioSystems, 6(8), 1338-1344 (2010-07-14)
3-Iodothyronamine (T(1)AM) is an endogenous thyroid hormone derivative with distinct biological effects that are largely opposite those of thyroid hormone. Administration of T(1)AM to rodents results in rapid and profound reduction in body temperature, heart rate, and metabolism. The structural
European journal of pharmacology, 793, 35-42 (2016-11-07)
3-iodothyronamine (T1AM) is a trace amine suspected to derive from thyroid hormone metabolism. T1AM was described as a ligand of G-protein coupled monoaminergic receptors, including trace amine associated receptors, suggesting the amine may exert a modulatory role on the monoaminergic
Thyroid : official journal of the American Thyroid Association, 26(12), 1656-1673 (2016-09-22)
Thyronamines (3-T
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