推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]/D -41 to -49°, c = 0.1 in ethanol
颜色
white to beige
溶解性
DMSO: 10 mg/mL, clear
储存温度
−20°C
SMILES字符串
O=C(N[C@@H](C(C)(C)C)C(N[C@H]([C@H](CN(CC1=CC=C(C2=NC=CC=C2)C=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)O)CC3=CC=CC=C3)=O)OC
InChI
1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
InChI key
AXRYRYVKAWYZBR-GASGPIRDSA-N
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一般描述
阿扎那韦抑制人免疫缺陷病毒中 gag 和 gag-pol 多蛋白的裂解。它被肝脏中的细胞色素 P450 吸收和代谢。它具有最小的副作用,并且对胰岛素敏感性和血清脂质谱没有影响。
生化/生理作用
阿扎那韦是一种抗病毒 HIV 蛋白酶抑制剂。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Daniel W Cole et al.
Experimental cell research, 382(1), 111386-111386 (2019-05-11)
Many FDA-approved anti-cancer therapies, targeted toward a wide array of molecular targets and signaling networks, have been demonstrated to activate the unfolded protein response (UPR). Despite a critical role for UPR signaling in the apoptotic execution of cancer cells by
Saif Ahmad Khan et al.
Pharmaceutics, 12(11) (2020-11-12)
Atazanavir (ATZ) presents poor brain availability when administered orally, which poses a major hurdle in its use as an effective therapy for the management of NeuroAIDS. The utilization of nanostructured lipid carriers (NLCs) in conjunction with the premeditated use of
Atazanavir
Croom KF, et al.
Drugs, 69(8), 1107-1140 (2009)
Atazanavir: new option for treatment of HIV infection
Havlir DV and O'marro SD
Clinical Infectious Diseases, 38(11), 1599-1604 (2004)
Jayanta Roy-Chowdhury et al.
Clinical pharmacology in drug development, 6(2), 140-146 (2017-03-07)
Hyperbilirubinemia is a common finding in individuals with a history of substance abuse. Although this may indicate a serious disorder of liver function, this is not always the case. An understanding of bilirubin formation, metabolism, and transport can provide a
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