所有图片(1)

主要文件

COO原产地证书/COA分析证书

安全信息

安全和法规

SML1624

JNJ-63533054

Name: JNJ-63533054
Brand: SIGMA

≥98% (HPLC)

别名:

(S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)benzamide

登录查看公司和协议定价

所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₇H₁₇ClN₂O₂

CAS号:

1802326-66-4

分子量:

316.78

UNSPSC代码:

12352200

NACRES:

NA.77

推荐产品

Slide 1 of 10

1 of 10

Sigma-Aldrich

R7772

核抑制剂

Sigma-Aldrich

SML0497

BQCA

Sigma-Aldrich

557364

罗斯科维汀(Roscovitine)

Sigma-Aldrich

300764

1,2,3,4-四氢-9H-吡啶并[3,4-b]吲哚

Sigma-Aldrich

SML1245

ML396

Sigma-Aldrich

C199

CGS-15943

Sigma-Aldrich

PZ0254

PF-06273340

Sigma-Aldrich

R8758

RPMI-1640 培养基

Sigma-Aldrich

286044

肉叶云香碱

Sigma-Aldrich

I2142

KN-62

质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D -89 to -99°, c = 1 in ethanol

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

储存温度

room temp

SMILES字符串

Clc1cc(ccc1)C(=O)NCC(=O)N[C@@H](C)c2ccccc2

InChI key

MWDVCHRYCKXEBY-LBPRGKRZSA-N

生化/生理作用

JNJ-63533054 is a potent and selective agonist of the orphan receptor hGPR139, a GPCR receptor expressed in the brain in circumventricular regions of the habenula and septum. JNJ-63533054 has an EC50 value of 16 nM, crosses the blood-brain barrier, and is orally available.

Potent and selective agonist of hGPR139 with an EC50 value of 16 nM