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质量水平
方案
≥95% (HPLC)
表单
powder
颜色
white to light brown
溶解性
DMSO: 5 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
ClC(C=C1)=CC=C1C2=NN(C(N3C(CCO)CCCC3)=CC(C)=N4)C4=C2
InChI
1S/C20H23ClN4O/c1-14-12-20(24-10-3-2-4-17(24)9-11-26)25-19(22-14)13-18(23-25)15-5-7-16(21)8-6-15/h5-8,12-13,17,26H,2-4,9-11H2,1H3
InChI key
TZWSGOPCLUTFBZ-UHFFFAOYSA-N
生化/生理作用
CMPPE is a GABAB receptor positive allosteric modulator (PAM).
CMPPE is a GABAB receptor positive allosteric modulator (PAM). GABAB receptor positive allosteric modulators have potential for treatment of many neuro-psychiatric disorders as well as drug dependence and seizures. The receptor is a GPCR expressed throughout the CNS; it acts as both an auto-receptor and heteroreceptor to mudulate GABA release and regulate K+ channels and Ca++ channels. CMPPE has the highest hypoactivity/anticonvulsant ratio.
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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