所有图片(1)
别名:
12-8039, Avalox, BAY12-8039, 盐酸盐
经验公式（希尔记法）:
C21H24FN3O4· HCl
CAS号:
分子量:
437.89
Beilstein:
8377447
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
powder
旋光性
[α]/D -119 to -139°, c = 0.5 in water
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 5 mg/mL, clear (warmed)
储存温度
−20°C
SMILES字符串
Cl.COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc4C(=O)C(=CN(C5CC5)c14)C(O)=O
InChI
1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H/t11-,16+;/m0./s1
InChI key
IDIIJJHBXUESQI-DFIJPDEKSA-N
正在寻找类似产品? 访问 产品对比指南
一般描述
莫西沙星是第四代合成氟喹诺酮类抗菌剂。莫西沙星与其他喹诺酮类药物不同，其是一种8-甲氧基喹诺酮。
应用
盐酸莫西沙星已被用于研究其对已生长至高密度细菌的抗菌作用。
生化/生理作用
莫西沙星已被证明可有效治疗鼻窦炎、社区获得性呼吸道感染、肺炎和慢性支气管炎的急性加重。与其他氟喹诺酮（如环丙沙星和氧氟沙星）相比，它具有更好的抗革兰氏阳性活性。莫西沙星可用于治疗细菌性皮肤感染。它可以适当渗透到周围组织和炎性液体中。氟喹诺酮类可通过与酶-DNA复合物结合来稳定由DNA回旋酶和拓扑异构酶IV产生的DNA链断裂。 与哺乳动物DNA促旋酶相比，莫西沙星对细菌DNA促旋酶的亲和力高100倍。莫西沙星是一种抗生素，可抗革兰氏阳性和革兰氏阴性细菌。莫西沙星在治疗耐多药结核病中的研究正在进行中。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Ana Topete et al.
Journal of controlled release : official journal of the Controlled Release Society, 326, 245-255 (2020-07-20)
Posterior capsule opacification (PCO) still remains the most frequent long term complication after cataract surgery, while endophthalmitis is rare but severe and should be prevented at all cost. Intraocular lenses (IOLs) with different designs (eg. edge and body-haptics angle) and
Understanding and sensitizing density-dependent persistence to quinolone antibiotics.
Gutierrez A, et al.
Molecular Cell, 68(6), 1147-1154 (2017)
An HPLC Method for the Determination of Moxifloxacin in Breast Milk by Fluorimetric Detection with Precolumn Derivatization.
Tekkeli SEK
Acta Chromatographica , 10-10 (2016)
Tomoko Hasunuma et al.
British journal of clinical pharmacology, 81(6), 1078-1090 (2016-01-17)
To examine whether strict control of clinical trial conditions could reduce apparent differences of pharmacokinetic (PK) parameters among ethnic groups. Open-label, single dose PK studies of moxifloxacin, simvastatin and meloxicam were conducted in healthy male subjects from three East Asian
Structural identification and characterization of impurities in moxifloxacin.
Kumar Y R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 34(5), 1125-1129 (2004)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门