推荐产品
质量水平
生物来源
(Paecilomyces lilacinus)
检测方案
≥95% (mixture of Leucinostatin A+B, HPLC)
形式
powder
溶解性
DMF: 10 mg/mL
DMSO: 10 mg/mL
ethanol: 10 mg/mL
methanol: 10 mg/mL
储存温度
−20°C
生化/生理作用
Leucinostatins A and B are the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus. Leucinostatins display broad bio-activity against gram-positive bacteria, fungi, plants and tumor cell lines. They play a role as uncouplers in the inner mitochondria membrane and inhibit mitochondrial ATP synthesis. Recently, interest in Leucinostatins has focused on other aspects such as understanding their activity: insulin-like growth factor I regulators, ionophore, inhibitors of cell surface expression of viral glycoproteins and their potent in vitro and in vivo anti-trypanosomal activity.
组分
Mixture of Leucinostatin A (Cas# 76600-38-9 / MF: C62H111N11O13) and Leucinostatin B (Cas# 76663-52-0 / MF: C61H109N11O13).
其他说明
Stable at −20 °C for at least 2 years.
分析物
说明
Leuconostatin A
Leucinostatin B
WGK
WGK 3
法规信息
新产品
Cell stress & chaperones, 25(2), 235-243 (2020-01-16)
Dysregulation of retinal pigment epithelium (RPE) cells is the main cause of a variety of ocular diseases. Potentially heat shock proteins, by preventing molecular and cellular damage and modulating inflammatory disease, may exert a protective role in eye disease. In
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