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![2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/235/567/dbf7ce48-3997-46a0-a6ad-8cc34ef0d39a/640/dbf7ce48-3997-46a0-a6ad-8cc34ef0d39a.png)
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 30 mg/mL, clear
储存温度
2-8°C
SMILES字符串
ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
InChI
1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI key
VYBFWKKCWTXCQX-UHFFFAOYSA-N
生化/生理作用
Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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