推荐产品
生物来源
insect
质量水平
表单
solution
浓度
0.1 mg/mL in DMSO
运输
ambient
储存温度
2-8°C
SMILES字符串
O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
InChI
1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
InChI key
DHZBEENLJMYSHQ-XCVPVQRUSA-N
生化/生理作用
It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.
Cantharidin inhibits protein phosphatase 2A.
其他说明
Stable for at least two years at 2-8° C.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
188.6 °F
闪点(°C)
87 °C
法规信息
高风险级别生物产品--毒素类产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Wei Li et al.
Cancer science, 101(5), 1226-1233 (2010-03-25)
Cantharidin is an active constituent of mylabris, a traditional Chinese medicine. It is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays an important role in control of cell cycle, apoptosis, and cell-fate determination. Owing to its
L Moed et al.
Archives of dermatology, 137(10), 1357-1360 (2001-10-27)
Cantharidin, a vesicant produced by beetles in the order Coleoptera, has a long history in both folk and traditional medicine. In dermatology, topical cantharidin has long been used to treat warts and molluscum. In 1962, cantharidin lost Food and Drug
Rolf Rauh et al.
Chinese medicine, 2, 8-8 (2007-07-06)
Herbal medicine is one of the forms of traditional medical practice. Traditional Chinese medicine (TCM) and traditional Vietnamese medicine (TVM) are well-known for their long-standing tradition of herbal medicine. Secreted by many species of blister beetle, most notably by the
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