推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]/D +45 to +60°, c = 1 in methanol
颜色
white to beige
溶解性
DMSO: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
C[C@]1(O[C@H](C(O)(C)C)CC1)[C@@]2([H])[C@@H](O)C[C@@]3(C)[C@]4([H])C[C@H](O)[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C6)[C@]46CC[C@@]32C
InChI
1S/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21-,22-,23-,26+,27-,28+,29-,30+/m0/s1
InChI key
WENNXORDXYGDTP-UOUCMYEWSA-N
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一般描述
环雌三醇从 黄芪 属物种中分离得到。
生化/生理作用
环雌三醇是从黄芪属物种中分离出的一种黄芪甲苷的糖苷配基,其具有抗炎特性,可促进伤口愈合和闭合伤口。 环雌三醇可增强人CD8+T淋巴细胞的抗病毒应答。 环雌三醇在人新生儿角质形成细胞、PC12细胞和原代神经元中可诱导端粒酶活性并诱导CREB(cAMP反应元件结合)激活。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种:
分析证书(COA)
Neuro-Signals, 22(1), 52-63 (2014-08-07)
Cycloastragenol (CAG) is an aglycone of astragaloside IV. It was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties. The present study demonstrates that CAG stimulates telomerase activity and cell proliferation in human neonatal keratinocytes. In
PloS one, 8(3), e58423-e58423 (2013-03-22)
The emergence of diseases associated with telomere dysfunction, including AIDS, aplastic anemia and pulmonary fibrosis, has bolstered interest in telomerase activators. We report identification of a new small molecule activator, GRN510, with activity ex vivo and in vivo. Using a
Journal of immunology (Baltimore, Md. : 1950), 181(10), 7400-7406 (2008-11-05)
Telomerase reverse transcribes telomere DNA onto the ends of linear chromosomes and retards cellular aging. In contrast to most normal somatic cells, which show little or no telomerase activity, immune cells up-regulate telomerase in concert with activation. Nevertheless, during aging
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