SML1379
Seratrodast
≥98% (HPLC)
别名:
(±)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid, AA-2414
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关于此项目
经验公式（希尔记法）:
C22H26O4
化学文摘社编号:
分子量:
354.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
产品名称
Seratrodast, ≥98% (HPLC)
InChI
1S/C22H26O4/c1-14-15(2)22(26)20(16(3)21(14)25)18(17-10-6-4-7-11-17)12-8-5-9-13-19(23)24/h4,6-7,10-11,18H,5,8-9,12-13H2,1-3H3,(H,23,24)
SMILES string
O=C(C(C)=C1C)C(C)=C(C(CCCCCC(O)=O)C2=CC=CC=C2)C1=O
InChI key
ZBVKEHDGYSLCCC-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
Quality Level
Gene Information
human ... TBXA2R(6915)
Biochem/physiol Actions
Seratrodast is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist with anti-asthmatic activity.
Seratrodast is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist with anti-asthmatic activity. Seratrodast inhibits the bronchconstriction induced by leukotriene D4 (LTD4), and platelet activating factor (PAF) with a long duration of action.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Margarita Rosa Romero-Imbachi et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 240, 108939-108939 (2020-11-10)
Centruroides margaritatus scorpion stings are common in Colombia. However, the cardiovascular toxicity of the venom has not been clarified. To study the effect and mechanisms of action of the complete venom of C. margaritatus (CmV) on the murine cardiovascular system.
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