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Merck
CN
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主要文件

安全信息

SML1370

Sigma-Aldrich

A-779 trifluoroacetate salt

≥98% (HPLC)

别名:

A779 trifluoroacetate salt, Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, D-Ala7-Ang-(1-7), DRVYIHA (Modification: Ala-7 = D-Ala), DRVYIHa trifluoroacetate salt, H-Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH trifluoroacetate salt, [7-D-ALA]-angiotensin-(1-7) trifluoroacetate salt

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About This Item

经验公式（希尔记法）:
C39H60N12O11 · xC2HF3O2
CAS号:
159432-28-7
分子量:
872.97 (free base basis)
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

lyophilized powder

颜色

white to off-white

运输

wet ice

储存温度

−20°C

生化/生理作用

A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC50 of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.
A-779 is a potent and selective antagonist of angiotensin (1-7).
This blocking angiotensin action affects cardiovascular function.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000163787
0000163787
0000159835
0000159835
0000130241

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Cardiovascular actions of angiotensin-(1-7)
Ferreira AJ and Santos RAS
Brazilian journal of medical and biological research, 38(4), 499-507 (2005)
Gustavo B Lamy et al.
Frontiers in physiology, 12, 682711-682711 (2021-07-30)
Central micturition control and urine storage involve a multisynaptic neuronal circuit for the efferent control of the urinary bladder. Electrical stimulation of the lateral preoptic area (LPA) at the level of the decussation of the anterior commissure in cats evokes

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