所有图片(1)
别名:
3-[[[[3- [4-[（甲基磺酰基）氨基]苯基] -4-氧代-4H-1-苯并吡喃-7-基]氧基]甲基]-苯甲酸, 3-[[[[3- [4-[（甲基磺酰基）氨基]苯基] -4-氧代-4H-铬基-7-基]氧基]甲基]苯甲酸, CVT 10216, GS 455534
经验公式（希尔记法）:
C24H19NO7S
推荐产品
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to beige
溶解性
DMSO: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O=C(O)C1=CC(COC2=CC=C3C(OC=C(C4=CC=C(NS(C)(=O)=O)C=C4)C3=O)=C2)=CC=C1
InChI
1S/C24H19NO7S/c1-33(29,30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12,14,25H,13H2,1H3,(H,27,28)
InChI key
YYOOFJZTRCPVFD-UHFFFAOYSA-N
一般描述
CVT-10216 是 5-Ht2c 激动剂。
生化/生理作用
CVT-10216 具有明确的抗焦虑特性。它不影响 mCPP（间氯苯基哌嗪）对运动活性的抑制。
CVT-10216 是乙醛脱氢酶 2（ALDH-2）的选择性可逆抑制剂，从而抑制多巴胺的合成。CVT-10216 可有效抑制酒精和可卡因的使用以及焦虑症。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Bin Yuan et al.
PloS one, 15(11), e0242809-e0242809 (2020-12-01)
The bone marrow microenvironment (BME) in acute myeloid leukemia (AML) consists of various cell types that support the growth of AML cells and protect them from chemotherapy. Mesenchymal stromal cells (MSCs) in the BME have been shown to contribute immensely
David H Overstreet et al.
Pharmacology, biochemistry, and behavior, 94(2), 255-261 (2009-09-15)
CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 that reduces excessive alcohol drinking. Anxiety plays a role in alcoholism. The present study asks whether CVT-10216 has anxiolytic properties, as reflected in social interaction behavior in four unrelated rodent models:
Simin Zhang et al.
Aesthetic plastic surgery, 44(3), 993-1005 (2020-01-19)
The cutaneous wound healing process mainly comprises re-epithelialization, fibrosis, and neovascularization. Impaired wound healing is common but tricky in plastic surgery. Aldehyde dehydrogenase 2 (ALDH2), the most effective subset of the ALDH enzyme family, is known to exert a major
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门