所有图片(1)
别名:
(2S,2′S)-2,2′-{[(5S,6R,7R,9R,11S,16R,18S,19S)-19-amino-11,16,18-trihydroxy-5,9-dimethylicosane-6,7-diyl]bis[oxy(2-oxoethane-2,1-diyl)]}disuccinic acid, Macrofusin
经验公式（希尔记法）:
C34H59NO15
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质量水平
生物来源
(Fusarium moniliforme)
形式
DMSO solution
浓度
1 mg/mL in DMSO
运输
dry ice
储存温度
−20°C
InChI
1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21+,22+,23+,24+,25-,26+,27-,32-/m1/s1
InChI key
UVBUBMSSQKOIBE-ZWKVXHQASA-N
一般描述
Fumonisin B1 is a mycotoxin found in the fungus Fusarium moniliforme. This toxin can also be obtained from corn infected with the same fungus. Fumonisin B1 shares similarities with sphingosine and okadaic acid (OA).
应用
Fumonisin B1 from Fusarium moniliforme has been used: as a standard in the analysis of mycotoxins in caecal content obtained from adult pigs, in the study of the effect of fumonisin B1 on the metabolism of prion protein (PrP) isoforms and the synthesis of scrapie prion protein PrPSc, and in the study of the toxic effects of fumonisin B1 on explants obtained from pig jejunum.
生化/生理作用
Fumonisin B1 is a fungal metabolite that acts as a hepatocarcinogen and causes hepatotoxicity in rats. In horses, Fumonisin B1 causes leukoencephalitis, and in pigs, it causes pulmonary edema syndrome. In China and southern parts of Africa, Fumonisin B1 is linked with high incidence of esophageal cancer in humans. Fumonisin B1 acts as an inhibitor of sphingosine N-acyltransferase enzyme.
WGK
WGK 1
闪点(°F)
188.6 °F
闪点(°C)
87 °C
法规信息
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