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Merck
CN

SML1141

Sigma-Aldrich

澳洲茄胺

≥95% (HPLC)

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别名:
(-)-Solasodine, (3β,22α,25R)-Spirosol-5-en-3-ol, NSC 178260, NSC 179187, Purapuridine, Solancarpidine, Solasod-5-en-3β-ol, Solasod-5-en-3β-ol (7CI,8CI), Solasodin
经验公式(希尔记法):
C27H43NO2
CAS号:
分子量:
413.64
EC 号:
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥95% (HPLC)

形式

powder

旋光性

[α]/D -88 to -98°, c = 0.2 in methanol

颜色

white to beige

溶解性

DMSO: 0.5 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES字符串

C[C@@H]1[C@]2(NC[C@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]

InChI

1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

InChI key

KWVISVAMQJWJSZ-VKROHFNGSA-N

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应用

Solasodine has been used in viability assays.

生化/生理作用

Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (GSH) levels, while reducing lipid peroxidation (LPO) and nitric oxide (NO) levels in the brains of ischemia/reperfusion (I/R)-injury model in rats. Also, Solasonine displayed multiple activities including, anti-cancer and leishmanicidal activities.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Agave negatively regulates YAP and TAZ transcriptionally and post-translationally in osteosarcoma cell lines
Ferraiuolo M, et al.
Cancer letters (2018)
Agave negatively regulates YAP and TAZ transcriptionally and post-translationally in osteosarcoma cell lines
Ferraiuolo M, et al.
Cancer Letters (2018)

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