SML1121
SB743921 hydrochloride
≥98% (HPLC)
别名:
N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methylbenzamide hydrochloride
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所有图片(1)
About This Item
经验公式（希尔记法）:
C31H33ClN2O3 · HCl
CAS号:
分子量:
553.52
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
H2O: 5 mg/mL, clear
储存温度
−20°C
SMILES字符串
CC(C)[C@@H](N(CCCN)C(C1=CC=C(C)C=C1)=O)C2=C(CC3=CC=CC=C3)C(C4=C(O2)C=C(Cl)C=C4)=O.Cl
InChI
1S/C31H33ClN2O3.ClH/c1-20(2)28(34(17-7-16-33)31(36)23-12-10-21(3)11-13-23)30-26(18-22-8-5-4-6-9-22)29(35)25-15-14-24(32)19-27(25)37-30;/h4-6,8-15,19-20,28H,7,16-18,33H2,1-3H3;1H/t28-;/m1./s1
InChI key
MLMZVWABFOLFGV-LNLSOMNWSA-N
生化/生理作用
SB743921 is an inhibitor of kinesin spindle protein (KSP) with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4, and CENP-E.
SB743921 is an inhibitor of kinesin spindle protein (KSP).
特点和优势
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Mehdi Bouhaddou et al.
Cell, 182(3), 685-712 (2020-07-10)
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds of thousands of people worldwide, highlighting an urgent need to develop antiviral therapies. Here we present a
商品
Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.
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