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质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]/D +25 to +40°, c = 0.2 in H2O
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 0.5 mg/mL, clear (warmed)
储存温度
−20°C
SMILES字符串
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1
InChI
1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
InChI key
QDGZDCVAUDNJFG-FXQIFTODSA-N
生化/生理作用
恩替卡韦是一种抗病毒鸟嘌呤类似物，可在病毒复制过程中抑制逆转录、DNA复制和转录。 恩替卡韦可用于治疗乙型肝炎。
恩替卡韦是一种抗病毒鸟嘌呤类似物，可抑制逆转录、DNA复制和转录。
恩替卡韦被用作治疗慢性乙型肝炎病毒（CHB）携带的拉米夫定难治性患者的有效药物（每日1 mg剂量）。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Wei Wei et al.
Cancer communications (London, England), 38(1), 61-61 (2018-10-12)
The optimal strategy for adjuvant therapy after curative resection for hepatocellular carcinoma (HCC) patients with solitary tumor and microvascular invasion (MVI) is controversial. This trial evaluated the efficacy and safety of adjuvant transcatheter arterial chemoembolization (TACE) after hepatectomy versus hepatectomy
Entecavir therapy for lamivudine?refractory chronic hepatitis B: improved virologic, biochemical, and serology outcomes through 96 weeks.
Sherman M, et al.
Hepatology, 48(1), 99-108 (2008)
Yunjian Zeng et al.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 24(4), 1414-1419 (2019-10-28)
To investigate the therapeutic effect of 125I seed implantation combined with chemotherapy and antiviral therapy on hepatitis B virus (HBV)-related liver cancer. A total of 126 patients with HBV-related liver cancer were selected and divided into observation group (n=63) and
Chia-Chi Wang et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 113(11), 786-793 (2013-08-06)
Several anti-viral drugs are approved for the treatment of hepatitis B virus (HBV) infection. However, whether quantitative hepatitis B surface antigen (qHBsAg) can predict the therapeutic response during long-term entecavir treatment remains unclear. Fifty-five chronic hepatitis B (CHB) patients who
Hideki Wakasugi et al.
Cancer letters, 434, 91-100 (2018-07-22)
Hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC). Nucleos(t)ide analogue (NA) therapy effectively reduces the incidence of HCC, but it does not completely prevent the disease. Here, we show that dysregulation of microRNAs (miRNAs) is
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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