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Merck
CN

SML1103

Sigma-Aldrich

恩替卡韦

≥98% (HPLC)

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别名:
2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-羟基-3-(羟甲基)-2-亚甲基环戊基] -6H-嘌呤-6-酮, 2-氨基-9-[((1S,3R,4S)-4-羟基-3-羟甲基-2-亚甲基-环戊基] -3,9-二氢嘌呤-6-酮, BMS 200475, SQ 34,676
经验公式(希尔记法):
C12H15N5O3
分子量:
277.28
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

旋光性

[α]/D +25 to +40°, c = 0.2 in H2O

储存条件

desiccated

颜色

white to beige

溶解性

H2O: 0.5 mg/mL, clear (warmed)

储存温度

−20°C

SMILES字符串

O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1

InChI

1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1

InChI key

QDGZDCVAUDNJFG-FXQIFTODSA-N

生化/生理作用

恩替卡韦是一种抗病毒鸟嘌呤类似物,可在病毒复制过程中抑制逆转录、DNA复制和转录。 恩替卡韦可用于治疗乙型肝炎。
恩替卡韦被用作治疗慢性乙型肝炎病毒(CHB)携带的拉米夫定难治性患者的有效药物(每日1 mg剂量)。

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Carc. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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