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Merck
CN

SML1078

Sigma-Aldrich

4-溴白藜芦醇

≥98% (HPLC)

别名:

5-[(1E)-2-(4-溴苯基)乙烯基] -1,3-苯二醇

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About This Item

经验公式(希尔记法):
C14H11BrO2
分子量:
291.14
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

储存条件

protect from light

颜色

, white to yellow to brown

溶解性

DMSO: 20 mg/mL, clear

储存温度

2-8°C

SMILES字符串

OC1=CC(/C=C/C2=CC=C(Br)C=C2)=CC(O)=C1

InChI

1S/C14H11BrO2/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,16-17H/b2-1+

InChI key

NCJVLKFAQIWASE-OWOJBTEDSA-N

一般描述

4-溴-白藜芦醇可通过与C位点以及另一个活性位点口袋的结合来阻断人sirtuin 1(sirt1)和sirt3的活性。

生化/生理作用

4-溴-白藜芦醇是一种可有效抑制Sirt1和Sirt3的白藜芦醇类似物。

特点和优势

该化合物是基因调控研究推荐产品。点击此处 ,查看更多基因调控精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问 sigma.com/discover-bsm

其他说明

感光的

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Biochemical pharmacology, 162, 154-168 (2018-11-11)
Albendazole (ABZ) is a microtubule-targeting anthelmintic that acts against a variety of human cancer cells, but the dependence of its cytotoxicity on non-mitotic effect remains elusive. Thus, we aimed to explore the mechanistic pathway underlying the cytotoxicity of ABZ in

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