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Merck
CN

SML1073

Sigma-Aldrich

BIX

≥98% (HPLC)

别名:

2-(3,4-二羟基苯基)-2-氧乙基酯硫氰酸, BiP蛋白诱导剂X

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About This Item

经验公式(希尔记法):
C9H7NO3S
分子量:
209.22
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

储存温度

2-8°C

SMILES字符串

OC1=C(O)C=C(C(CSC#N)=O)C=C1

InChI

1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2

InChI key

SVFLBLCWKKQKDW-UHFFFAOYSA-N

应用

BIX已被用于细胞活力检测。

生化/生理作用

BIX(BiP蛋白诱导因子X)可诱导内质网伴侣蛋白GRP78(葡萄糖调节蛋白78,BiP)的表达,导致未折叠蛋白应答的减弱。 BIX可保护神经元细胞和视网膜细胞免受内质网应激诱导的细胞死亡。

其他说明

空气敏感

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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