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Merck
CN

SML1065

Sigma-Aldrich

TR100

≥98% (HPLC)

别名:

2-Cyano-3-[1-[3-(dimethylamino)propyl]-2-methyl-1H-indol-3-yl]-N-octyl-2-propenamide

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About This Item

经验公式(希尔记法):
C26H38N4O
分子量:
422.61
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 5 mg/mL, clear (warmed)

储存温度

2-8°C

SMILES字符串

CC1=C(/C=C(C#N)\C(NCCCCCCCC)=O)C2=C(N1CCCN(C)C)C=CC=C2

InChI

1S/C26H38N4O/c1-5-6-7-8-9-12-16-28-26(31)22(20-27)19-24-21(2)30(18-13-17-29(3)4)25-15-11-10-14-23(24)25/h10-11,14-15,19H,5-9,12-13,16-18H2,1-4H3,(H,28,31)/b22-19-

InChI key

XXRLIGWROLDOLS-QOCHGBHMSA-N

生化/生理作用

TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells.
TR100 is a specific anti-tropomyosin agent that preferentially disrupts the actin cytoskeleton of tumor cells. TR100 selectively disrupts Tm5NM1/2 containing actin filaments. TR100 induces apoptosis in a panel of neural crest-derived tumor cell lines with no adverse effects on cardiac structure and function.

危险声明

预防措施声明

危险分类

Aquatic Chronic 4

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Katharina Baron et al.
PloS one, 11(11), e0164284-e0164284 (2016-11-11)
Quantitative magnetic resonance imaging (qMRI) offers several advantages in imaging and determination of soft tissue alterations when compared to qualitative imaging techniques. Although applications in brain and muscle tissues are well studied, its suitability to quantify relaxation times of intact

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