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Merck
CN

SML1002

Sigma-Aldrich

青藤碱 盐酸盐

≥98% (HPLC)

别名:

(9a,13a,14a)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one hydrochloride, Cucoline hydrochloride, Kukolin hydrochloride

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About This Item

经验公式(希尔记法):
C19H23NO4 · HCl
CAS号:
分子量:
365.85
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

生物来源

plant (Sinomenium acutum)

质量水平

检测方案

≥98% (HPLC)

形式

powder

旋光性

[α]/D -70 to -90°, c = 1 in H2O

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

颜色

white to beige

溶解性

H2O: 20 mg/mL, clear

储存温度

2-8°C

SMILES字符串

OC1=C(OC)C=CC(C2)=C1[C@]3(CC(C(OC)=C4)=O)[C@@]4([H])[C@H]2N(C)CC3.Cl

InChI

1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1

InChI key

YMEVIMJAUHZFMW-VUIDNZEBSA-N

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生化/生理作用

Sinomenine is a herbal medicine used to treat inflammatory diseases like rheumatoid arthritis. Sinomenine had anti-inflammatory effects in several animal models of inflammation, and inhibits mast cell degranulation and histamine release. Additionally, Sinomenine potentiates renewal of human embryonic stem cells.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Yuting Xu et al.
Artificial cells, nanomedicine, and biotechnology, 47(1), 4131-4138 (2019-11-09)
Background: Accumulating evidence displays that sinomenine hydrochloride (SH) are utilised to treat a variety of cancers. Nevertheless, the influences of SH on ovarian cancer stay blurry. We endeavoured to uncover the antitumor effects of SH on ovarian cancer and underlying

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