product name
虾青素, ≥97% (HPLC), from Blakeslea trispora
生物来源
Blakeslea trispora
质量水平
检测方案
≥97% (HPLC)
形式
powder
储存条件
desiccated
protect from light
颜色
, pink to very dark purple
溶解性
DMSO: 1 mg/mL (warmed)
储存温度
−20°C
InChI
1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
InChI key
MQZIGYBFDRPAKN-UWFIBFSHSA-N
一般描述
虾青素（AST）是一种红色的膳食类胡萝卜素。它主要存在于水生动物和微藻中，如雨生红球藻（Haematococcus pluvialis）和小球藻（Chlorella zofingiensis）。
应用
虾青素已被用于：
- 作为抗氧化剂来研究其对臂尾轮虫（Brachionus manjavacas）（轮虫纲）种群生长的影响
- 研究其对糖尿病性视网膜病变治疗的影响。
- 通过人前列腺 LNCaP 细胞的表观遗传修饰，研究其在恢复 Nrf2（核因子红细胞 2 p45 相关因子 2）和谷胱甘肽 S-转移酶 P1（GSTP1）表达中的作用。
生化/生理作用
体内和体外研究提出虾青素（AST）具有促进健康的活性，表明其可用于预防多种疾病，例如癌症和帕金森病。由于其颜色鲜红，AST 已用作动物饲料中的食用色素。
虾青素是一种有效的抗氧化剂，具有抗增殖、神经保护和抗炎作用。 虾青素可防止氧化应激，抑制 NF-KB，抑制促炎基因，抑制促炎化合物一氧化氮、前列腺素 E2、TNF-α 和白细胞介素-1β 的产生。 虾青素′对 TNF-α 和棕榈酸产生的氧化应激的保护作用已被证明可以改善胰岛素抵抗。 虾青素也被证明是 PPARγ 的抑制剂。
其他说明
光和空气敏感
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth.
Johnston R K, et al.
Aquaculture Research, 49(6), 2278-2287 (2018)
Shreya Agrawal et al.
Plant physiology (2021-10-09)
The high-value carotenoid astaxanthin (3,3'-dihydroxy-β,β-carotene-4,4'-dione) is one of the most potent antioxidants in nature. In addition to its large-scale use in fish farming, the pigment has applications as a food supplement and an active ingredient in cosmetics and in pharmaceuticals
Rita Giovannetti et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 73(1), 157-162 (2009-03-13)
The aggregation of astaxanthin in hydrated methanol was kinetically studied in the temperature range from 10 degrees C to 50 degrees C, at different astaxanthin concentrations and solvent composition. A kinetic model for the formation and transformation of astaxanthin aggregated
Patrizia Casella et al.
Antioxidants (Basel, Switzerland), 9(5) (2020-05-18)
Haematococcus pluvialis microalgae is a promising source of astaxanthin, an excellent antioxidant carotenoid. H. pluvialis, as well as other species, could find more extensive applications as healthy food for a variegated carotenoids composition in addition to astaxanthin. Official method has
Chengzhen Liu et al.
Journal of agricultural and food chemistry, 67(18), 5113-5121 (2019-04-24)
Astaxanthin, a hydrophobic carotenoid found in marine plants and animals, is claimed to exhibit various beneficial biological activities. Its use as a nutraceutical in foods, however, is currently limited by its low water-solubility and poor bioavailability. The goal of this
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