一般描述
Bantag-1 是一种肽拮抗剂。溶于水溶液。
生化/生理作用
Bantag-1 是孤儿 GPCR 铃蟾肽受体亚型 3（BRS-3）的高特异性、高亲和力的拮抗剂。 Bantag-1 在 BRS-3 表达细胞中的结合亲和力为 1.3 nM。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor.
Nakamura T, et al.
Biochemical Pharmacology, 115, 64-76 (2016)
Xiao-Ming Guan et al.
Cell metabolism, 11(2), 101-112 (2010-01-26)
Bombesin receptor subtype 3 (BRS-3) is a G protein coupled receptor whose natural ligand is unknown. We developed potent, selective agonist (Bag-1, Bag-2) and antagonist (Bantag-1) ligands to explore BRS-3 function. BRS-3-binding sites were identified in the hypothalamus, caudal brainstem
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