所有图片(1)
别名:
(2S)- 1-[[5-(2-Fluorophenyl)-2-methyl-4-thiazolyl]carbonyl]-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-pyrrolidine (9CI), (S)-1-[5-[2-Fluorophenyl]-2-methylthiazol-4-yl]-1-[2-[[5-phenyl-[1,3,4]oxadiazol-2-yl]methyl]pyrrolidin-1-yl]methanone, SB-674042
经验公式（希尔记法）:
C24H21FN4O2S
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质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to beige
溶解性
DMSO: 10 mg/mL, clear
储存温度
2-8°C
InChI
1S/C24H21FN4O2S/c1-15-26-21(22(32-15)18-11-5-6-12-19(18)25)24(30)29-13-7-10-17(29)14-20-27-28-23(31-20)16-8-3-2-4-9-16/h2-6,8-9,11-12,17H,7,10,13-14H2,1H3/t17-/m0/s1
InChI key
HYBZWVLPALMACV-KRWDZBQOSA-N
生化/生理作用
SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity to OX1R and mediates intracellular calcium flux in OX1R-expressing cells.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Xiaocen Chang et al.
Pancreas, 48(4), 568-573 (2019-04-05)
The study aimed to investigate the involvement of the mammalian target of rapamycin (mTOR) signaling pathway in orexin-A/OX1 receptor-induced insulin secretion in rat insulinoma INS-1 cells. Rat insulinoma INS-1 cells were grown and treated with various concentrations of orexin-A, with
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