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Merck
CN

SML0891

L-152,804

≥98% (HPLC)

别名:

5,5-Dimethyl-2-(2,3,4,9-tetrahydro-­3,3-dimethyl-1oxo-1H-xanthen-9-yl)-1,3-cyclohexane­dione, 5,5-Mmethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-1,3 cyclohexanedione, 9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone, L-152804, L152804

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关于此项目

经验公式(希尔记法):
C23H26O4
化学文摘社编号:
分子量:
366.45
UNSPSC Code:
12352200
NACRES:
NA.77
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产品名称

L-152,804, ≥98% (HPLC)

InChI

1S/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19,24H,9-12H2,1-4H3/t19-/m0/s1

InChI key

CCJIUBMPDVWYLU-IBGZPJMESA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

L-152,804 is a potent and selective non-peptide neuropeptide Y Y5 receptor antagonist.
L-152,804 is a potent and selective non-peptide neuropeptide Y Y5 receptor antagonist. L-152,804 induces a potent reduction of food intake in rodents.

Features and Benefits

This compound is featured on the Neuropeptide Y Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M C R Gumbs et al.
Neuroscience, 447, 28-40 (2019-12-31)
The preclinical multicomponent free-choice high-fat high-sucrose (fcHFHS) diet has strong validity to model diet-induced obesity (DIO) and associated maladaptive molecular changes in the central nervous system. fcHFHS-induced obese rats demonstrate increased sensitivity to intracerebroventricular infusion of the orexigenic Neuropeptide Y
Shiba Yousefvand et al.
Canadian journal of physiology and pharmacology, 96(12), 1301-1307 (2018-10-17)
Neuropeptide Y (NPY) plays a mediatory role in cerebral insulin function by maintaining energy balance. The current study was designed to determine the role of insulin in food intake and its interaction with NPY receptors in 8 experiments using broiler

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