质量水平
检测方案
≥95% V basis
形式
powder
储存条件
protect from light
颜色
faintly yellow to dark yellow
溶解性
H2O: 20 mg/mL, clear
储存温度
−20°C
SMILES字符串
O=[V]123([N]4=CC=CC5=C4C6=C(C=CC=[N]62)C=C5)(OO3)OO1.[K]
InChI
1S/C12H8N2.K.2H2O2.O.V/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;2*1-2;;/h1-8H;;2*1-2H;;/q;+1;;;;
InChI key
MQPXOTNOFVCXDA-UHFFFAOYSA-N
生化/生理作用
bpV(phen)是一种胰岛素受体激酶(IRK)激活剂和蛋白质磷酸酪氨酸磷酸酶抑制剂,具有对PTEN、磷酸酶和张力蛋白同源物的选择性,而后者是一种参与细胞周期调节的肿瘤抑制磷酸酶。bpV(phen)对PTEN的IC50值为38 nM,而PTPβ为343 nM、PTP-1β为920 nM。bpV(phen)在氧化应激中具有抗炎作用,包括对氧化应激诱导的心肌细胞损伤的抑制作用,可以通过ROS对PTEN的作用部分调节。它也可能参与分化。
bpV(phen)(双过氧双(二吡啶)氧钒酸钾)可通过介导NO依赖性杀微生物作用而对利什曼病的疾病进展显示出保护作用。
其他说明
光敏性
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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