所有图片(1)
别名:
K2 [VO(O2)2C6H4NO2] · 2 H2O, 过氧钒二钾 (pic) 二水合物, 过氧（吡啶）氧钒酸二钾 (V) 二水合物
经验公式（希尔记法）:
K2VOO2O2C6H4NO2 · 2H2O
推荐产品
质量水平
检测方案
≥95% V basis
形式
powder
储存条件
protect from light
颜色
faintly yellow to dark yellow
溶解性
H2O: 20 mg/mL, clear
储存温度
−20°C
应用
已将 bpV (pic) 用于细胞培养处理，研究 HERV（人内源性逆转录病毒）转录所需的多条通路的激活途径。
生化/生理作用
bpV (pic) 含有一个极性侧链，特异性抑制 PTEN（磷酸酶和张力蛋白同源物），与其母体化合物不同，后者也靶向其他几种磷酸酶。因此，使得 bpV (pic) 成为一种更好的抑制剂。 bpV (pic) 被认为是多发性硬化症（一种自身免疫性疾病）相关的人内源性逆转录病毒的强效激活剂。
bpV (pic) 是一种蛋白磷酸酪氨酸磷酸酶的双过氧钒抑制剂，对磷酸酶和张力蛋白同源物 (PTEN) 具有选择性，PTEN 是一种参与细胞周期调控的肿瘤抑制磷酸酶。PTEN 的 bpV (pic) IC 50 值为 31 nM，相比之下，PTPβ 为 12.7 μM，PTP-1β 为61μM。bpV (pic) 也可作为胰岛素类似物和激活胰岛素受体激酶 (IRK)。
其他说明
光敏性
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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