product name
嘌吗啡胺, ≥98% (HPLC)
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL, clear (warmed)
储存温度
−20°C
InChI
1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)
InChI key
FYBHCRQFSFYWPY-UHFFFAOYSA-N
应用
Purmorphamine已被用于研究Tupfel长鳍株斑马鱼中Hedgehog信号通路上调的影响。
生化/生理作用
Purmorphamine可直接结合Smoothened（Smo）受体，激活Hedgehog（Hh）信号通路。多项研究已经显示，Purmorphamine可诱导成骨细胞的分化、从人胚胎干细胞中产生心肌细胞、增加人纹状体神经干细胞系的神经元分化、以及将人脐带间充质干细胞（hUCMSC）分化成运动神经元。
警示用语：
Warning
危险声明
危险分类
Muta. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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