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Merck
CN
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文件

SML0851

Sigma-Aldrich

GZ-793A

≥98% (HPLC)

别名:

(R)-3-[2,6-cis-Di(4-methoxyphenethyl)piperidin-1-yl]propane-1,2-diol hydrochloride, 3-[(2R,6S)-2,6-Bis[2-(4-methoxyphenyl)ethyl]-1-piperidinyl]-(2R)-1,2-propanediol hydrochloride

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About This Item

经验公式（希尔记法）:
C26H37NO4 · HCl
CAS号:
1356447-90-9
分子量:
464.04
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

H2O: 3 mg/mL, clear

储存温度

2-8°C

InChI

1S/C26H37NO4.ClH/c1-30-25-14-8-20(9-15-25)6-12-22-4-3-5-23(27(22)18-24(29)19-28)13-7-21-10-16-26(31-2)17-11-21;/h8-11,14-17,22-24,28-29H,3-7,12-13,18-19H2,1-2H3;1H/t22-,23+,24-;/m1./s1

InChI key

FLFFCQKGCYZDOI-SJUVJREQSA-N

生化/生理作用

GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2), which transports the monoamine neurotransmitters from cellular cytosol into synaptic vesicles. GZ-793A is 50-fold selective for VMAT over the serotonin or dopamine transporters. VMAT2 has recently been considered a target for the treatment of methamphetamine abuse. In rat studies, GZ-793A decreased self-administration of methamphetamine with no development of tolerance.

象形图

Environment
GHS09

警示用语：

Warning

危险声明

H410

预防措施声明

P273 - P391 - P501

危险分类

Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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