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Merck
CN
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主要文件

安全信息

SML0828

Sigma-Aldrich

FPH2

≥98% (HPLC)

别名:

4-(3-(5-Chloro-2-methoxyphenyl)thioxureido)-1-ethyl-1H-pyrazole-3-carboxamide, 4-[[[(5-Chloro-2-methoxyphenyl)amino]thioxomethyl]amino]-1-ethyl-1H-pyrazole-3-carboxamide, BRD-9424

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About This Item

经验公式（希尔记法）:
C14H16ClN5O2S
CAS号:
957485-64-2
分子量:
353.83
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 10 mg/mL, clear

储存温度

−20°C

SMILES字符串

S=C(Nc2c[n](nc2C(=O)N)CC)Nc1c(ccc(c1)Cl)OC

InChI

1S/C14H16ClN5O2S/c1-3-20-7-10(12(19-20)13(16)21)18-14(23)17-9-6-8(15)4-5-11(9)22-2/h4-7H,3H2,1-2H3,(H2,16,21)(H2,17,18,23)

InChI key

PCHRYHSDDPPZBV-UHFFFAOYSA-N

生化/生理作用

FPH2 (BRD-9424) induced functional proliferation of primary human hepatocytes in vitro.
FPH2 (BRD-9424) induced functional proliferation of primary human hepatocytes in vitro. Human induced pluripotent stem (iPS) cells can be differentiated toward hepatocyte-like (iHep) cells, but replication is not great, and cells typically show an immature hepatic phenotype and have limited use as a renewable source of functional human hepatocytes. FPH2 induced hepatocyte doublings at a rate consistent with reported liver regeneration kinetics. FPH2 can be used in conjunction with FH1 (BRD-K4477), which induces a more mature phenotype.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
093M4720V

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