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SML0784

BMS-303141

≥98% (HPLC), ATP citrate lyase inhibitor, powder

别名:

3,5-二氯-2-羟基-N-(4-甲氧基[1,1′-联苯]-3-基)苯磺酰胺

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关于此项目

经验公式（希尔记法）:
C19H15Cl2NO4S
化学文摘社编号:
943962-47-8
分子量:
424.30
NACRES:
NA.77
UNSPSC Code:
51111800
MDL number:
MFCD25976797
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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产品名称

BMS-303141, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=S(NC1=C(OC)C=CC(C2=CC=CC=C2)=C1)(C3=C(O)C(Cl)=CC(Cl)=C3)=O

InChI

1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3

InChI key

SIIPNDKXZOTLEA-UHFFFAOYSA-N

Application

BMS-303141已被用于抑制乳腺癌细胞系中的ATP柠檬酸裂合酶。

Biochem/physiol Actions

BMS-303141是ATP柠檬酸裂解酶（ACL）的一种有效抑制剂。 BMS-303141可抑制HepG2细胞中的脂质合成，IC50值为8μM。同时，在鼠高脂血症模型中，其可降低血浆中的甘油三酸酯的含量。
BMS-303141是ATP柠檬酸裂解酶（ACL）的一种有效抑制剂。

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000466958
0000466958
0000189944
0000189945
0000153622

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全球贸易项目编号

货号GTIN
SML0784-5MG04061833058510
SML0784-25MG04061833058503