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质量水平
方案
≥95% (HPLC)
表单
powder
旋光性
[α]/D 10 to 15°, c = 1 in H2O
储存条件
desiccated
颜色
off-white to gray-brown
溶解性
H2O: 15 mg/mL, clear
储存温度
−20°C
SMILES字符串
O=C1C2=CC=CC=C2N=CN1CC(C[C@@H]3[C@@H](O)CCCC3)=O.C
InChI
1S/C17H20N2O3.CH4/c20-13(9-12-5-1-4-8-16(12)21)10-19-11-18-15-7-3-2-6-14(15)17(19)22;/h2-3,6-7,11-12,16,21H,1,4-5,8-10H2;1H4/t12-,16+;/m1./s1
InChI key
SNTOTCUGCWLHEZ-KKJWGQAZSA-N
生化/生理作用
Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inhibitor of prolyl-transfer RNA synthetase (ProRS).
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
The chemistry and biology of febrifugine and halofuginone.
McLaughlin N P, et al.
Bioorganic & Medicinal Chemistry, 22(7), 1993-2004 (2014)
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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