SML0494
VU0361737
≥98% (HPLC)
别名:
CID-44191096, ML128, N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
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关于此项目
经验公式（希尔记法）:
C13H11ClN2O2
化学文摘社编号:
分子量:
262.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
VU0361737, ≥98% (HPLC)
InChI
1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
SMILES string
COc1cc(NC(=O)c2ccccn2)ccc1Cl
InChI key
ARYUXFNGXHNNDM-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
film
color
white
solubility
DMSO: 15 mg/mL (clear solution)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
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