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质量水平
方案
≥98% (HPLC)
表单
film
颜色
white
溶解性
DMSO: 15 mg/mL (clear solution)
储存温度
2-8°C
SMILES字符串
COc1cc(NC(=O)c2ccccn2)ccc1Cl
InChI
1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChI key
ARYUXFNGXHNNDM-UHFFFAOYSA-N
生化/生理作用
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
商品
Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.
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