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主要文件

COO原产地证书/COA分析证书

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安全信息

安全和法规

SML0475

CGP36742

Name: CGP36742
Brand: SIGMA

≥97% (NMR)

别名:

P-(3-Aminopropyl)-P-butyl-phosphinic acid, SGS 742

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About This Item

经验公式（希尔记法）:

C₇H₁₈NO₂P

CAS号:

123690-78-8

分子量:

179.20

MDL编号:

MFCD00882735

UNSPSC代码:

12352200

PubChem化学物质编号:

329825430

NACRES:

NA.77

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质量水平

100

方案

≥97% (NMR)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

H₂O: 10 mg/mL (clear solution, warmed)

储存温度

room temp

SMILES字符串

CCCCP(O)(=O)CCCN

InChI

1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10)

InChI key

ONNMDRQRSGKZCN-UHFFFAOYSA-N

生化/生理作用

CGP36742 is a GABAB receptor antagonist.

CGP36742 was the first orally active GABAB-selective antagonist. The IC₅₀ for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.