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Merck
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文件

SML0446

Sigma-Aldrich

A-419259 trihydrochloride

≥98% (HPLC)

别名:

7-[Trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride, A419259 trihydrochloride

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About This Item

经验公式（希尔记法）:
C29H34N6O · 3HCl
CAS号:
364042-47-7
分子量:
592.00
MDL编号:
MFCD19690922
UNSPSC代码:
12352200
PubChem化学物质编号:
329824728
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

储存条件

desiccated

颜色

white to beige

溶解性

H2O: 10 mg/mL (clear solution)

储存温度

room temp

SMILES字符串

Cl.Cl.Cl.CN1CCN(CC1)[C@H]2CC[C@@H](CC2)n3cc(-c4ccc(Oc5ccccc5)cc4)c6c(N)ncnc36

InChI

1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;

InChI key

ALRMEQIQFCUAMR-KOONDFAVSA-N

生化/生理作用

A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Src Family Kinases Overview

Src is the original member of a group of non-receptor protein-tyrosine kinases termed the Src family kinases (SFKs). Learn about the SFKs that, in humans, consist of eight members, a small group of atypical members, and two related kinases.

Discover Bioactive Small Molecules for Kinase Phosphatase Biology

Discover Bioactive Small Molecules for Kinase Phosphatase Biology

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