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方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: >5 mg/mL (warmed)
储存温度
−20°C
SMILES字符串
CC(F)(F)CN1CCOc2c(nn(-c3ccccc3Cl)c2-c4ccc(Cl)cc4)C1=O
InChI
1S/C21H17Cl2F2N3O2/c1-21(24,25)12-27-10-11-30-19-17(20(27)29)26-28(16-5-3-2-4-15(16)23)18(19)13-6-8-14(22)9-7-13/h2-9H,10-12H2,1H3
InChI key
FJMQJSUOOGOWBD-UHFFFAOYSA-N
生化/生理作用
PF-514273 is a highly selective CB1 antagonist.
PF-514273 is a highly selective CB1 antagonist. The Ki for binding to CB1 and CB2 receptors is 1 nM and 10 mM, respectively. PF-514273 inhibits food intake and weight gain in rodents.
特点和优势
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
商品
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