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Merck
CN
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文件

SML0337

Sigma-Aldrich

S-烯丙基-L-半胱氨酸

≥98% (HPLC)

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别名:
L-脱氧阿洛糖, S-烯丙基-半胱氨酸, S-烯丙基半胱氨酸, SAC
经验公式（希尔记法）:
C6H11NO2S
CAS号:
21593-77-1
分子量:
161.22
MDL编号:
MFCD00151975
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
329825342
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

旋光性

[α]/D -8 to -15°, c = 1 in H2O

颜色

white to beige

溶解性

H2O: >10 mg/mL

储存温度

−20°C

SMILES字符串

N[C@@H](CSCC=C)C(O)=O

InChI

1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1

InChI key

ZFAHNWWNDFHPOH-YFKPBYRVSA-N

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一般描述

S-烯丙基- L -半胱氨酸具有抗炎特性。它抑制氧化强化剂酶并螯合金属。S-烯丙基- L -半胱氨酸具有降血糖和降低胆固醇的作用。 它可以防止细胞凋亡，降低诱导型一氧化氮合酶的活性，并阻断核因子κB的活性。

生化/生理作用

S-烯丙基-L-半胱氨酸是在大蒜中发现的含硫氨基酸，具有抗氧化、抗癌、抗肝毒、神经保护和神经营养活性。S-烯丙基-L-半胱氨酸在缺血性损伤和阿尔茨海默病等多种动物模型中具有有效活性。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Hayate Javed et al.
Brain research, 1389, 133-142 (2011-03-08)
S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in
Patricia Rojas et al.
The Journal of nutritional biochemistry, 22(10), 937-944 (2010-12-31)
S-Allylcysteine (SAC), the most abundant organosulfur compound in aged garlic extract, has multifunctional activity via different mechanisms and neuroprotective effects that are exerted probably via its antioxidant or free radical scavenger action. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse has been the most widely
Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease: Prevention and Therapy (2014)
J Yu et al.
Placenta, 33(6), 487-494 (2012-03-13)
Preeclampsia (PE) is a major cause of fetal growth restriction and perinatal mortality, which involves oxidative stress and vasodilator signaling disorder. S-allyl-L-cysteine (SAC) is one of the most abundant compounds in garlic extracts, and possesses several biological activities. This research
Man-Hui Pai et al.
The British journal of nutrition, 108(1), 28-38 (2011-10-21)
Oral cancer is prevalent worldwide. Studies have indicated that an increase in the osteopontin (OPN) plasma level is correlated with the progression of oral cancer. Our previous report showed that the aqueous garlic extract S-allylcysteine (SAC) inhibited the epithelial-mesenchymal transition
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