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SML0332

Sigma-Aldrich

依地芬

≥95% (HPLC)

别名:

1-十八烷基-2-甲基甘油-3-磷酸胆碱, 4-羟基-7-甲氧基-N,N,N-三甲基-3,5,9-三氧四-4-磷庚烷-1-氧化铵-4-氧化物, ALP, ET 18-OCH3, ET-18-OMe, NSC 324368, NSC 343649, Ro 14-5243, 外消旋1-O-十八烷基-2-O-甲基甘油-3-磷酸胆碱

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CN¥1,377.65
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5 MG
CN¥1,377.65
25 MG
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About This Item

经验公式（希尔记法）:
C27H58NO6P
CAS号:
70641-51-9
分子量:
523.73
MDL编号:
MFCD00135190
UNSPSC代码:
12352200
PubChem化学物质编号:
329825337
NACRES:
NA.77

CN¥1,377.65

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质量水平

100

方案

≥95% (HPLC)

表单

powder

颜色

white to beige

溶解性

H2O: 15 mg/mL (clear solution)

运输

wet ice

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OC

InChI

1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3

InChI key

MHFRGQHAERHWKZ-UHFFFAOYSA-N

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
G1046P3017341207
Edelfosine ≥95% (HPLC)

SML0332

Edelfosine

[6]-Gingerol ≥98% (HPLC)

G1046

[6]-Gingerol

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine ≥95.5% (GC), ≥98% (TLC)

P3017

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine

ET-18-OCH3 A cell-permeable and reversible cytotoxic agent that shows selective cytocidal activity against neoplastic cells and virally transformed cells.

341207

ET-18-OCH3

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥95.5% (GC), ≥98% (TLC)

assay

≥95% (TLC)

form

powder

form

-

form

powder

form

solid

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 15 mg/mL (clear solution)

solubility

methanol: 1 mg/mL, clear, colorless

solubility

-

solubility

DMSO: 5 mg/mL, ethanol: 5 mg/mL, chloroform: 50 mg/mL, water: soluble

color

white to beige

color

-

color

-

color

white

一般描述

依地福新具有抗炎、抗自身免疫、抗寄生虫和抗病毒的特性。它通过细胞收缩和细胞膜扰乱来刺激红细胞衰亡。[1]

应用

依地福新已用于治疗人肺癌 A549 细胞，并研究其对 Tuftelin 1（TUFT1）表达的影响。[2]它还用于评估 MCF-7/M 细胞的细胞生长。[3]

生化/生理作用

依地福新是一种合成烷基-赖氨磷脂，具有抗肿瘤活性。
依地福新是一种合成烷基-赖氨磷脂，具有抗肿瘤活性。该化合物诱导多种癌细胞的凋亡。乙二胺嘧啶在细胞膜中积累，在细胞膜中改变脂质成分并诱导脂质筏和 Fas/CD95 死亡受体的共簇。

特点和优势

这种化合物是激酶磷酸酶生物学研究的特色产品。点击此处发现更多特色激酶磷酸酶生物产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000313994
    0000151073
    0000151073
    0000313994
    0000055921

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    Monica Rapino et al.
    Nanomaterials (Basel, Switzerland), 9(7) (2019-06-30)
    Dental pulp stem cells (DPSCs) represent a population of stem cells which could be useful in oral and maxillofacial reconstruction. They are part of the periendothelial niche, where their crosstalk with endothelial cells is crucial in the cellular response to
    The phenomenon of acquired resistance to metformin in breast cancer cells: The interaction of growth pathways and estrogen receptor signaling
    Scherbakov AM, et al.
    IUBMB Life, 68(4), 281-292 (2016)
    Joo Hee Choi et al.
    Colloids and surfaces. B, Biointerfaces, 181, 879-889 (2019-08-07)
    In this study, a double network hydrogel of a natural polysaccharide gellan gum (GG) hydrogel and a synthetic hydrogel poloxamer-heparin (PoH) hydrogel (PoH/GG DNH) is introduced to complement disadvantages of each hydrogel and improve the microenvironment for cell delivery. The
    Edelfosine Induced Suicidal Death of Human Erythrocytes
    Briglia M, et al.
    Cellular Physiology and Biochemistry, 37(6), 2221-2230 (2015)
    Xiaolin Xu et al.
    Experimental animals, 68(3), 371-380 (2019-04-05)
    Ketogenic diet (KD) has been used in epilepsy for decades, but previous studies found it may cause severe bone loss. Every-other-day ketogenic diet (EODKD), the combination of KD with intermittent fasting, showed better potential for seizure control recently, while its
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