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一般描述
苯基丁酸钠刺激尿中氮元素排出。它是一种前体药物,经过 β-氧化后形成乙酸苯酯。苯基丁酸钠用于处理尿素循环疾病。它可能和月经失调,闭经和食管和胃的疼痛性粘膜炎有关。
应用
苯基丁酸钠用于作为内质网(ER)压力抑制物,用来研究ER压力在 betatrophin表达中的作用。
生化/生理作用
苯基丁酸钠是一种组蛋白去乙酰化酶抑制剂。
特点和优势
该化合物是基因调控研究的特色产品。点击此处以了解更多的基因调控特色产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问sigma.com/discover-bsm。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control
Lee B, et al.
Molecular Genetics and Metabolism, 100(3), 221-228 (2010)
Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies
Lee YH, et al.
Scientific Reports, 6(3), 24013-24013 (2016)
Xiujing Dou et al.
Food & nutrition research, 62 (2018-12-24)
Host defense peptides (HDPs) possess direct antibacterial, antineoplastic, and immunomodulatory abilities, playing a vital role in innate immunity. Dietary-regulated HDP holds immense potential as a novel pathway for preventing infection. In this study, we examined the regulation mechanism of HDPs
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease (2008)
Advances in Clinical Chemistry, Volume 17 (2014)
商品
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
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