SML0295
二氢杨梅素
≥98% (HPLC)
别名:
(2R,3R)-3,5,7-三羟基-2-（3,4,5-三羟基苯基）-2,3-二氢色-4-酮, 3,3′,4′,5,5′,7-六羟基黄烷酮, DHM, 蛇葡萄素
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关于此项目
经验公式（希尔记法）:
C15H12O8
化学文摘社编号:
分子量:
320.25
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
SMILES string
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(C(O)=C3)O)[C@H]1O
InChI key
KJXSIXMJHKAJOD-LSDHHAIUSA-N
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to beige
solubility
DMSO: ≥5 mg/mL (warmed)
storage temp.
−20°C
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General description
二氢杨梅素是显齿蛇葡萄中的主要类黄酮物质。
Application
二氢杨梅素已用于研究其对分化好的3T3-L1前脂肪细胞中的脂肪生成和葡萄糖摄取的影响。它还用于研究其抗肝癌细胞的抗肿瘤活性。
Biochem/physiol Actions
二氢杨梅素 (Ampelopsin) 是一种具有抗氧化和抗癌活性的黄烷醇。
二氢杨梅素 (Ampelopsin) 是一种具有抗氧化和抗癌活性的黄烷醇，具有抗酒精中毒作用。 它的抗酒精作用似乎是由于它在苯并二氮杂卓位点作为 GABA-A受体的正调节剂的作用。
二氢杨梅素具有抗炎作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Scott A Snyder et al.
Nature, 474(7352), 461-466 (2011-06-24)
Although much attention has been devoted to resveratrol, a unique polyphenol produced by plants and credited as potentially being responsible for the 'French paradox'--the observation that French people have a relatively low incidence of coronary heart disease, even though their
Jun Zhou et al.
Journal of separation science, 34(2), 160-168 (2011-01-20)
A simple, rapid and specific method based on cloud-point extraction (CPE) was developed to determine ampelopsin in rat plasma after oral administration by reversed-phase high-performance liquid chromatography. The non-ionic surfactant Genapol X-080 was chosen as the extract solvent. Some important
Li-Ping Ruan et al.
Journal of pharmaceutical and biomedical analysis, 38(3), 457-464 (2005-06-01)
The aim of this study was to increase the solubility of ampelopsin (AMP) in water by two systems: solid dispersions with polyethylene glycol 6000 (PEG 6000) or polyvinylpyrrolidone K-30 (PVP K30) and inclusion complexes with beta-cyclodextrin (BCD) and hydroxypropyl-beta-cyclodextrin (HPBCD).
Baolai Zhang et al.
Anti-cancer drugs, 23(6), 590-596 (2012-01-14)
The aim of this study was to establish xenograft models of tumor in mice bladder and evaluate the antitumor efficacy of ampelopsin sodium (Amp-Na). A total of 2×10 human bladder carcinoma EJ cells and murine sarcoma 180 cells were instilled
Jiantao Ye et al.
Planta medica, 74(3), 252-257 (2008-02-27)
Human immunodeficiency virus (HIV) infection can result in oxidative stress through production of reactive oxygen species (ROS). Simultaneously, oxidative stress is able to activate the replication of virus and lead to the apoptosis of T lymphocytes which is the defense
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