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Merck
CN

SML0247

Sigma-Aldrich

利扎曲坦 苯甲酸盐

≥98% (HPLC)

别名:

MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt

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About This Item

经验公式(希尔记法):
C15H19N5 · C7H6O2
分子量:
391.47
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

H2O: ≥5 mg/mL

储存温度

room temp

SMILES字符串

OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23

InChI

1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

InChI key

JPRXYLQNJJVCMZ-UHFFFAOYSA-N

基因信息

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生化/生理作用

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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Rizatriptan is effective for headache in a patient with meningeal carcinomatosis.
Takeshi Satow et al.
Journal of pain and symptom management, 41(5), e2-e4 (2011-04-05)
Iain P Fraser et al.
Headache, 52(4), 625-635 (2012-02-01)
To evaluate the pharmacokinetic profile and tolerability of single doses of rizatriptan oral disintegrating tablets (ODTs) in pediatric migraineurs. Acute migraine treatment options for children are limited despite a rising migraine prevalence. No triptans are approved in those under 12
Types of colitis based on histology.
Muhammed Sherid et al.
Disease-a-month : DM, 57(9), 457-489 (2011-09-29)
Zhao Dong et al.
Brain research, 1368, 151-158 (2010-10-26)
The trigeminovascular nociception induced by electrical stimulation of the dura mater surrounding the superior sagittal sinus in anesthetized animals has been widely used as a model for investigation of the pathophysiology of vascular headache such as migraine. However, little is
Robert MacNeill et al.
Bioanalysis, 4(10), 1163-1173 (2012-06-02)
In the context of matrix effects in bioanalytical LC-MS/MS, a speculative link between free cholesterol, the recoveries of the compound from three common extraction procedures, and response enhancement was qualitatively investigated. Injections on-column of cholesterol both in solution and extracts

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