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![4-{[(4-METHYLPHENYL)SULFONYL]OXY}BUTYL 4-METHYLBENZENESULFONATE AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/208/494/a5122b67-8573-4730-83f8-8a65b4e244a2/640/a5122b67-8573-4730-83f8-8a65b4e244a2.png)
方案
≥98% (HPLC)
表单
powder
drug control
psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
颜色
off-white to light brown
溶解性
H2O: ≥5 mg/mL at 60 °C
储存温度
2-8°C
InChI
1S/C16H23NO.ClH/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14;/h7-10,15H,3-6,11-12H2,1-2H3;1H
InChI key
MWRACNBZNVAJHE-UHFFFAOYSA-N
应用
Pyrovalerone hydrochloride may be used in dopamine-mediated cell signaling studies.
生化/生理作用
Pyrovalerone hydrochloride is a CNS Stimulant; norepinephrine-dopamine reuptake inhibitor (NDRI)
Pyrovalerone hydrochloride is a rapidly-absorbed psychostimulant. It belongs to the class of synthetic cathinones often used as performance-enhancing agent by athletes before being banned.
Pyrovalerone is a norepinephrine-dopamine reuptake inhibitor (NDRI) that acts as a CNS stimulant.
特点和优势
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - STOT SE 3
靶器官
Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Jane M Prosser et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8(1), 33-42 (2011-11-24)
Synthetic cathinones have recently emerged and grown to be popular drugs of abuse. Their dramatic increase has resulted in part from sensationalized media attention as well as widespread availability on the Internet. They are often considered "legal highs" and sold
Peter C Meltzer et al.
Journal of medicinal chemistry, 49(4), 1420-1432 (2006-02-17)
Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian system. These three neurotransmitters have been the focus of considerable research because the modulation of their production and their interaction at monoamine receptors has profound effects upon a multitude
David J Lapinsky et al.
Bioorganic & medicinal chemistry, 17(11), 3770-3774 (2009-05-16)
Non-tropane-based photoaffinity ligands for the dopamine transporter (DAT) are relatively unexplored in contrast to tropane-based compounds such as cocaine. In order to fill this knowledge gap, a ligand was synthesized in which the aromatic ring of pyrovalerone was substituted with
Sabina Strano-Rossi et al.
Rapid communications in mass spectrometry : RCM, 24(18), 2706-2714 (2010-09-04)
A method for the toxicological screening of the new designer drug methylenedioxypyrovalerone (MDPV) is described; with an emphasis on its application for anti-doping analysis. The metabolism of MDPV was evaluated in vitro using human liver microsomes and S9 cellular fractions
The metabolism of pyrovalerone hydrochloride.
W Michaelis et al.
Journal of medicinal chemistry, 13(3), 497-503 (1970-05-01)
商品
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