质量水平
检测方案
≥98% (HPLC)
形式
powder
旋光性
[α]/D +90 to +106° in methanol (c=1)
储存条件
desiccated
颜色
white to tan
溶解性
DMSO: ≥8 mg/mL at 60 °C
创始人
Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度
2-8°C
SMILES字符串
O.[Na+].CC(C)(O)c1ccccc1CC[C@@H](SCC2(CC2)CC([O-])=O)c3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3
InChI
1S/C35H36ClNO3S.Na.H2O/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);;1H2/q;+1;/p-1/b15-10+;;/t32-;;/m1../s1
InChI key
QAXHQHBRRJHZHL-ZPQUALOVSA-M
应用
孟鲁司特钠水合物已被用作阳性对照药物，用于研究Gumiganghwal-tang水提取物（GGTA）对气道炎症和肺纤维化的保护作用。
生化/生理作用
孟鲁司特钠水合物是一种白三烯受体拮抗剂（LTRA），用于维持哮喘的治疗和缓解季节性过敏症状。它是亚型特异性CysLT1受体拮抗剂。
特点和优势
该化合物是由Merck & Co., Inc., Kenilworth, NJ, U.S.开发的。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。
这种化合物是 ADME 毒性研究的特色产品。点击此处了解更多特色 ADME 毒性产品。可访问sigma.com/discover-bsm了解更多关于生物活性小分子的其他研究领域。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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